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Fabrication of an electrochemical biosensor based on Fe3O4 nanoparticles and uricase modified carbon paste electrode for uric acid determination

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dc.contributor.authorErdogan, Zehra Ozden
dc.contributor.authorKucukkolbasi, Semahat
dc.date.accessioned2026-10-09T21:46:58Z
dc.date.issued2021
dc.departmentYüksek İhtisas Üniversitesi
dc.description.abstractA novel uric acid biosensor based on Fe3O4 nanoparticles (Fe(3)O(4)NPs) modified carbon paste electrode is described. Electron transfer characteristics of bare (CPE) and Fe3O4NP-modified carbon paste electrodes (Fe3O4/CPE) were studied by cyclic voltammetry and electrochemical impedance spectroscopy. The voltammetric study indicated that the incorporation of Fe(3)O(4)NPs into carbon paste increased the electroactive surface area of the electrode and improved electron transfer. Under the optimum working conditions, the purposed biosensor showed a linear response to uric acid from 0.16 mM to 2.11 mM with a detection limit of 0.08 mM. The biosensor exhibited high selectivity, good repeatability, reproducibility, and stability. Moreover, the construction and renewal procedure of the purposed biosensor is simple and inexpensive. [GRAPHICS]
dc.description.sponsorshipSelcuk University Scientific Project [12201026]
dc.description.sponsorshipThis work is supported by Selcuk University Scientific Project (Project no: 12201026).
dc.identifier.doi10.1007/s00706-021-02749-z
dc.identifier.endpage314
dc.identifier.issn0026-9247
dc.identifier.issn1434-4475
dc.identifier.issue3
dc.identifier.orcid0000-0002-5129-5385
dc.identifier.scopus2-s2.0-85102060449
dc.identifier.scopusqualityQ3
dc.identifier.startpage309
dc.identifier.urihttps://doi.org/10.1007/s00706-021-02749-z
dc.identifier.urihttps://hdl.handle.net/20.500.12794/3441
dc.identifier.volume152
dc.identifier.wosWOS:000625068000001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynak.digerScience Citation Index Expanded (SCI-EXPANDED)
dc.language.isoen
dc.publisherSpringer Wien
dc.relation.ispartofMonatshefte Fur Chemie
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.relation.sdgGoal-03: Good Health and Well-Being
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260922
dc.subjectBiosensor
dc.subjectCarbon Paste Electrode
dc.subjectUric Acid
dc.subjectFe3O4 Nanoparticle
dc.titleFabrication of an electrochemical biosensor based on Fe3O4 nanoparticles and uricase modified carbon paste electrode for uric acid determination
dc.typeArticle

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