Predictive roles of interpeduncular and pontomesencephalic angle measurements, which are anatomical landmarks in cranial MRI, in the differential diagnosis of pediatric headache

Abstract

Aim: This study aims to comparatively assess the interpeduncular and pontomesencephalic angles in the cranial magnetic resonance imaging (MRI) images of pediatric\rheadache patients. Thus, we think that it will contribute to the studies to be conducted\rfor the objective evaluation of pediatric headache requiring the use of cerebral MRI.\rMaterials and Methods: This retrospective study was performed using clinical and\rradiological data extracted from the medical files of 157 patients and 49 controls. Our\rpopulation consisted of 101 females (49 %) and 105 males (51 %). The patient population was divided into 4 categories as follows: non-specific headache (thought to be of\rthe tension-type), vasovagal syncope, sinusitis, and epilepsy. Interpeduncular (IP) and\rpontomesencephalic (PM) angles of patients and control groups were compared on MR\rimages.\rResults: The population average age in this series was 11.05 ± 3.78 (range, 5 to 17) years.\rThe comparison of IP angleyielded statistically significant differences between tensiontypeheadache-epilepsy, tension type-headache- vasovagal syncope, epilepsy-control, and\rvasovagal syncope-control groups. Multiple comparisons for PM angle demonstrated remarkable differences between headache-control, epilepsy-control, epilepsy-sinusitis, and\rcontrol- vasovagal syncope groups.\rConclusion: Our results indicated that measurements of IP and PM angles on the cerebral MRI views of children whose etiology could not be clarified and for whom cranial\rimaging was required, may yield valuable data in the differential diagnosis. We are of\rthe opinion that by working on larger data sets in the future, more valuable data can be\robtained in differential diagnosis.