Retrospective Analysis of the Treatment of Patients with Acute Stroke in a Training and Research Hospital

Abstract

Aim: This study aimed to evaluate the indications for intravenous recombinant tissue plasminogen activator (IV r-tPA) and/or mechanicalthrombectomy in patients with acute stroke and the research intended to determine why these treatments were not applied in some cases.Materials and Methods: This study included 300 stroke patients treated between January 2018 and June 2019 for whom the data wereaccessible. The patients with acute stroke were retrospectively examined with regards to demographic and clinical information.Results: Of the 300 patients, 142 (47%) were females and 158 (52%) were males and 214 patients (71%) were admitted to the hospital withinthe first 4.5 hours. The mean age of the patients was 68.11±13.15 years (34-94 years). Moreover, 58 (19%) patients did not receive IV r-tPA and/or undergo mechanical thrombectomy owing to contraindications.Conclusion: In this study, we determined that the most common reason for not applying IV r-tPA and/or mechanical thrombectomy wasthe inability of some patients to reach the hospital within the treatment window. Multi-centre studies are needed to investigate the variousfactors contributing to the delay in accessing treatment for patients with acute ischaemic stroke. Addressing these issues may increase theproportion of patients receiving thrombolytic therapy and/or undergoing mechanical thrombectomy.