Association of inflammation markers with epicardial adipose tissue in drug naive metabolic syndrome

Abstract

The metabolic syndrome (MetS) or syndrome X is a serious health problem effecting an increasing number of person worldwide. In the present study, the aim was to investigate whether there is an association among epicardial adipose tissue thickness, insulin resistance, lymphocyte to monocyte ratio (LMR) and monocyte count-to-high density lipoprotein cholesterol ratio (MHR) levels in drug naive patient with metabolic syndrome. Twenty-two consecutive drug-naive women diagnosed with MetS and 30 age matched consecutive healthy women (as the control group) were recruited Into the study. MHR was significantly higher [12.1 (10.5-16.4) vs 10.3 (7.0-13.8); p <0.01], whereas LMR was significantly lower in patients with MetS [3.6 (2.5-4.1) vs [4.1 (3.3-5.9) p = 0.02]. The present study shows that both LMR and MHR may be novel and useful indicators of MetS.