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The effect of black mulberry (Morus nigra) consumption on cognition in patients with mild-to-moderate Alzheimer's dementia: A pilot feasibility study

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dc.contributor.authorOz, Yeliz Guccer
dc.contributor.authorNaharci, Mehmet Ilkin
dc.contributor.authorCelebi, Fatih
dc.contributor.authorRakicioglu, Neslisah
dc.contributor.authorGoktas, Zeynep
dc.date.accessioned2026-10-09T21:47:56Z
dc.date.issued2024
dc.departmentYüksek İhtisas Üniversitesi
dc.description.abstractThe purpose of this study was to test the feasibility and the possible effects of black mulberry on cognitive functions in Alzheimer's disease (AD). A total of 39 participants aged 65+ with mild-to-moderate AD were involved and 20 subjects were administered 20g of black mulberry concentrate daily for 12 weeks (intervention group), while 19 received no intervention (control group). Cognitive assessment utilized with MiniMental State Examination (MMSE) and AD Assessment Scale-Cognitive Subscale (ADAS-Cog) tests; Geriatric Depression Scale (GDS-15) used for depression screening. At the end of the study, although MMSE scores decreased (p = 0.003) and GDS-15 scores increased (p = 0.034) in control group, there was no change in intervention group. On the contrary, ADAS-Cog scores decreased in intervention group (p = 0.002) while the control group showed no improvement. This study showed that treatment of black mulberry (Morus nigra) for 12 weeks may slightly improve cognitive function in patients with AD. (c) 2023 Elsevier Inc. All rights reserved.
dc.description.sponsorshipScienti fic and Technological Research Council of Turkey (TUBITAK) grant [TUBITAK- 1002-120S160]
dc.description.sponsorshipThis study was supported by a The Scienti fic and Technological Research Council of Turkey (TUBITAK) grant (Grant No: TUBITAK 1002-120S160) .
dc.identifier.doi10.1016/j.gerinurse.2023.11.014
dc.identifier.endpage236
dc.identifier.issn0197-4572
dc.identifier.issn1528-3984
dc.identifier.pmid38052130
dc.identifier.scopus2-s2.0-85179080081
dc.identifier.scopusqualityQ2
dc.identifier.startpage229
dc.identifier.urihttps://doi.org/10.1016/j.gerinurse.2023.11.014
dc.identifier.urihttps://hdl.handle.net/20.500.12794/3517
dc.identifier.volume55
dc.identifier.wosWOS:001134939700001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynak.digerScience Citation Index Expanded (SCI-EXPANDED); Social Science Citation Index (SSCI)
dc.language.isoen
dc.publisherMosby-Elsevier
dc.relation.ispartofGeriatric Nursing
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.relation.sdgGoal-03: Good Health and Well-Being
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260922
dc.subjectAnthocyanin
dc.subjectAlzheimer Disease
dc.subjectBlack Mulberry
dc.subjectAntioxidant
dc.subjectFlavonoid
dc.titleThe effect of black mulberry (Morus nigra) consumption on cognition in patients with mild-to-moderate Alzheimer's dementia: A pilot feasibility study
dc.typeArticle

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